Job Description

• Drug metabolism and pharmacokinetics – Bioanalysis (in vitro and invivo).
• In-vitro ADME studies like Metabolic stability, Intrinsic metabolic clearance, Plasma stability, Plasma protein binding, Brain protein binding, Solubility studies, Log-D, PAMPA.
• PK-PD studies in rat and mice of NCEs ( worked in obesity and neurosciences)
• Bio-analytical method development & validation for Novel Chemical Entities in complex biological matrix like plasma, serum, tissues, on HPLC and LCMS/MS
• Handling of laboratory animals like rat, mice, Guniea Pig and Rabbits.
• Dose administration to experimental animals by different routes like oral (p.o.), intravenous (i.v.), intraperitoneal (i.p.), subcutaneous (SC) etc.
• Data analysis, Data generation, compilation and report preparation
• Canulation of jugular vein, bile duct and femoral vein in experimental rat model.
• Experience with small animal surgery and handling.
• Good knowledge In vivo animal models.
• Proficiency in compound dose preparation, administration to experimental animals.
• Flexibility, and the ability to work in fast paced and team oriented environment.
• Preparation & Review of study protocol, study reports and SOPs for DMPK studies.
• Excellent organizational and guidance skills to team associates.
• Highly developed problem-solving skills.
• Good Documentation Practices and GLP Compliance.

• Drug metabolism and pharmacokinetics – Bioanalysis (in vitro and invivo).
• In-vitro ADME studies like Metabolic stability, Intrinsic metabolic clearance, Plasma stability, Plasma protein binding, Brain protein binding, Solubility studies, Log-D, PAMPA.
• PK-PD studies in rat and mice of NCEs ( worked in obesity and neurosciences)
• Bio-analytical method development & validation for Novel Chemical Entities in complex biological matrix like plasma, serum, tissues, on HPLC and LCMS/MS
• Handling of laboratory animals like rat, mice, Guniea Pig and Rabbits.
• Dose administration to experimental animals by different routes like oral (p.o.), intravenous (i.v.), intraperitoneal (i.p.), subcutaneous (SC) etc.
• Data analysis, Data generation, compilation and report preparation
• Canulation of jugular vein, bile duct and femoral vein in experimental rat model.
• Experience with small animal surgery and handling.
• Good knowledge In vivo animal models.
• Proficiency in compound dose preparation, administration to experimental animals.
• Flexibility, and the ability to work in fast paced and team oriented environment.
• Preparation & Review of study protocol, study reports and SOPs for DMPK studies.
• Excellent organizational and guidance skills to team associates.
• Highly developed problem-solving skills.
• Good Documentation Practices and GLP Compliance.

Jubilant Drug Discovery and Development Services (JDDDS) , is part of the Jubilant LifeSciences family of companies with R&D Centers in India, USA and business offices in Asia, Europe and North America. JDDDS has a global reach and provides comprehensive drug discovery and development solutions from target discovery to clinical development in partnership with leading pharma companies worldwide.

With clear scientific focus in Oncology, Metabolic Disorders, CNS and Pain and Inflammation, JDDDS has rapidly emerged as a leading collaborator for pharma industry. In each of these therapeutic areas, Jubilant has developed a depth of expertise in discovery informatics, medicinal chemistry, structural biology, biology, in vitro, in vivo models and translational sciences. Combined with strong clinical development and manufacturing capabilities, Jubilant has emerged as a fully integrated company with end-to-end solution for pharma industry.

JDDDS business constitutes three Jubilant subsidiaries, Jubilant Biosys (Drug discovery services), Jubilant Chemsys (Chemistry services) and Jubilant Clinsys (Clinical trial services). With over 1200 highly skilled and experienced scientific and medical personnel spread across Bangalore and Noida in India, Europe and the US, the JDDDS vertical leverages the capabilities in emerging markets for a global outcome, accelerating the global drug development efforts.